2025 NFL Draft Odds & Best Bets: Predictions, Props, and Picks to Watch

Next to the start of the season and the Super Bowl, the NFL Draft may be the most anticipated event of the year. Like any good NFL-related event, you can bet on it — and sportsbooks have a wide range of NFL Draft markets for bettors to choose from.

However, much like the Super Bowl, it can be easy to get lost in the sea of NFL Draft markets for which sportsbooks have odds posted. As always, we’re here to help. Check out our Best Bets list for the 2025 NFL Draft (odds via FanDuel).

NFL Draft Odds: Picks 1–4

I’m not going to bother with no-brainer picks like who will go No. 1 overall. At -20000, there is no value in betting on Cam Ward (QB, Miami). You could argue there’s value in other players, but Ward will go No. 1.

Historically, the first pick of the NFL Draft is not a surprise.

It would be a shock if the Browns took anyone other than Travis Hunter (WR/DB, Colorado) at No. 2 (-1200). Consequently, we can expect the Giants to go with Abdul Carter (DL, Penn State) at No. 3 (-650) and Will Campbell (OT, LSU) at No. 4 to the Patriots. New England is the wildcard, with defensive-minded Mike Vrabel considering other options and shopping for offensive linemen later.

Odds of Going at No. 5: Fade Ashton Jeanty

Boise State running back Ashton Jeanty is favored at -170, giving him a 62.96% chance. But I think Jeanty at No. 5 is just media-driven speculation — not unlike the buzz that had the Colts taking Will Levis at No. 4 back in 2023.

Instead, the Colts took who they were expected to take before the rumor mill went nuts: Anthony Richardson.

With that in mind, bet on Michigan DT Mason Graham (+195) to go at No. 5 to the Jaguars. He’s the consensus favorite in mock drafts and the player the Jags were expected to take before the speculation got loud.

With the No. 6 Pick in the NFL Draft…

I have to go with Ashton Jeanty here (+230). Armand Membou (OT) is favored (+105), and he would be a smart pick for new Raiders head coach Pete Carroll. But Jeanty just seems like the kind of running back Carroll would love — and know how to use.

NFL Draft Odds: College Props (odds via DraftKings)

Total Big Ten Players Selected in First Round, O/U 9.5 at +110/-140

Most of the mock drafts I’ve reviewed have eight or nine players from the Big Ten going in the first round. I didn’t read one that had 10-plus. However, mock drafts are typically no better than 40% accurate, and there are a handful of Big Ten players projected to go early in the second round who could easily slide into the first.

I wouldn’t fault anyone for going with the under, but I’m a sucker for plus-money odds and think there’s a good chance we see 10 Big Ten players go in the first. Take the over.

Total SEC Players Selected in First Round, O/U 14.5 at -200/+150

The SEC had 11 players selected in the first round last year, but most of the mock drafts I’ve seen have them projected to get 15-plus this year. That doesn’t leave a margin for error — but when it comes to the SEC and the NFL Draft, I’m always going with the over.

NFL Draft Odds: Team to Draft Shedeur Sanders

Oh, where, oh, where will Shedeur Sanders go? Oh, where, oh, where will he be? New York (+320) and Cleveland (+380) have been in the conversation, but both are expected to take someone else in the first round.

Next to them, the two most talked-about destinations have been Pittsburgh (+185) and New Orleans (+410). The market is largely counting on him going in the first round. The conversation widens if he slips into the second.

The Steelers haven’t seemed eager to use their first-round pick on a quarterback, and they may be more interested in Jaxson Dart or Tyler Shough anyway. That means Sanders will fall into the second round — which will bring the Browns and Giants back into play.

Since the Browns have the first pick in the second round, I don’t think they can resist reuniting Travis Hunter and Sanders. I’m taking the Browns at +380.